Strain Model Specification

Il1b-Luc-2A-EGFP

Strain Name C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Catalog Number NM-KI-00010
Genetic Background C57BL/6Smoc
Gene Symbol Il1b
Strain State Repository Live
Research Application Inflammation and immunity,gene tracing

Validation Data

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Fig1. IL1β reporter gene expression in the mice was monitored through noninvasive molecular imaging. IL1 β  in the mouse body was activated through LPS  treatment.

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Fig2. Analysis of EGFP expresssion in PBMC by FACS. The homozygous KI mouse expresses EGFP in  F4/80+ macrophages in peripheral blood.

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Fig3. Analysis of EGFP expresssion in the spleen by FACS. The homozygous KI mouse expresses EGFP in F4/80+ macrophages in the spleen.

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Fig4. Analysis of EGFP expresssion in the liver by FACS. The homozygous KI mouse expresses EGFP in F4/80+ macrophages in the liver.