Strain Model Specification

Il22-Cre

Strain Name C57BL/6Smoc-Il22em1(Linker-iCre-PolyA(SV40)Smoc
Catalog Number NM-KI-200167
Genetic Background C57BL/6Smoc
Gene Symbol Il22
Synonyms IL-22, Iltif, IL-22a, ILTIFa
NCBI ID 50929 ↗
MGI ID 1355307 ↗
Ensembl ID ENSMUSG00000074695 ↗
Strain State Sperm cryopreservation
Research Application The cytokine interleukin-22 (IL-22) plays an important role in tissue regeneration and maintenance of skin and mucosal barriers．

Validation Data

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Fig. 1 CreERT2-mediated recombination in the intestine of IL22Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the lymph nodes of IL22Cre/+; Rosa26tdTomato/+ mouse. 

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Fig. 2 Detection of tdTomato(red) in various tissues of IL22Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the lymph nodes of thymus, intestine and individual cells of testicular interstitium and cerebral cortex. TdTomato can not be detected in the kidney, heart, lung and liver. (For more detailed information please contact our technical advisor.)