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Krt14-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-190024

Strain Name : C57BL/6Smoc-Krt14^{em2(CreERT2-Wpre-polyA)Smoc}

Gene Summary

Gene Name

Synonyms :
Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14
NCBI ID :
16664
MGI ID :
96688
Ensembl ID :
ENSMUSG00000045545
Strain State :
活体

Model Description

A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene.

Validation Data

微信截图_20190716101355.png

Fig1 CreERT2-mediated recombination in Skin, Tongue & Esophagus of Krt14 CreERT2+/-;R26 tdTomato+/- mice.

A， Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B， Krt14-CreERT2+/-; Rosa26 tdTomato+/-

C， Rosa26 tdTomato+/-

微信截图_20190716101755.png

Fig2 Confocal images showing expression of tdTomato in Skin, Tongue & Esophagus of Krt14 CreERT2+/-;R26 tdTomato +/- mice.

A， Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B， Krt14-CreERT2+/-; Rosa26 tdTomato+/-

C， Rosa26 tdTomato+/-

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