Lgr5-2A-DreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-200178

Strain Name : C57BL/6Smoc-Lgr5em1(2A-DreERT2)Smoc

Gene Summary

Gene Name

Model Description

A 2A-DreERT2 expression cassette was knocked into the Lgr5 gene stop codon site.

Validation Data

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+;R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Glutamine synthetase (GS, green) is expressed in a rim of hepatocytes surrounding hepatic veins. (Documented in the following reference.)


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