Ly6g-Cre-2A-tdTomato

Background : C57BL/6Smoc

Catalog : NM-KI-200219

Strain Name : C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc

Gene Summary

Gene Name

Model Description

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Validation Data

image.pngFig1. Cre mediated recombination in spleen of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse.

image.png

Fig2. Detection of tdTomato(red) and zsGreen(green) in various tissues of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse. Expression tissues include: spleen, thymus, colon. A few cells expressed in liver, stomach, kidney, small intestine and adrenal gland. Tissues that unexpressed include brain, spinal cord, eyeballs, heart, lung, salivary glands, brown fat, pituitary gland, pancreas, uterus and ovaries, muscle, skin. (5-week old, female) 

No obvious positive signals were detected in the tissue for tdTomato. (For more detailed information please contact our technical advisor.)

image.pngFig3. Detection of Ly6G and tdTomato expression on neutrophils in peripheral blood in WT and HE Ly6g-Cre-2A-tdTomato KI mice. 

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