MC38-hHER3

Background : MC38

Catalog : NM-S13-TM49

Strain Name :

MC38-Igs2em1(hHER3)Smoc

Gene Summary

Gene Name

Model Description

A HER3 expression cassette was knocked into the H11 locus.

Validation Data

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Fig1. hHER3 expression on in vitro cultured cells of MC38-hHER3.

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Fig2. In vivo validation of MC38-hHER3 in C57BL/6 mice.

C57BL/6 mice were inoculated with MC38-hHER3 subcutaneously at 1×106 cells/mouse inoculum for tumor development.

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Fig3. hHER3 expression in tumors after in vivo growth of MC38-hHER3 in wild type C57BL/6 mice.

The tumors were collected at day 33 post tumor cell inoculation.

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