MC38-hROR1

Background : MC38

Catalog : NM-S13-TM58

Strain Name :

MC38-Igs2em1(hROR1)Smoc

Gene Summary

Gene Name

Model Description

A ROR1 expression cassette was knocked into the H11 locus.

Validation Data

image.png

Fig.1 hROR1 expression on in vitro cultured cells of MC38-hROR1

image.png



Fig.2 In vivo validation of MC38-hROR1 in C57BL/6 mice.C57BL/6 mice were inoculated with MC38-hROR1 subcutaneously at 3×106 cells/mouse inoculum for tumor development. The day of vaccination for mice is defined as Day 0, and tumor measurement and weight measurement begin on the 6th day after vaccination, twice a week.

image.png



Fig.3 hROR1 expression in tumors after in vivo growth of MC38-hROR1 in wild type C57BL/6 mice.The tumors were collected at day 48 post tumor cell inoculation. When the MTV reaches 1000-1500mm3, take 2 tubes from each group and send them to FACS for testing (Markers: L/D, mCD45, hROR1).

Related Strains

Product
Product Catalog
Background
NMC-230112
CT26
Inquire
NMC-230113
MC38
Inquire
NMC-230086
MC38
Inquire
NM-GA01-TM05
<span style="text
Inquire
NMC-230086
MC38
Inquire
NMC-230087
CT26
Inquire
NM-GS03-1
NCI
Inquire
NM-N02
SH
Inquire
NM-F08-1
HCC827
Inquire
NM-F10-1
NCI
Inquire
Email Back to top