Strain Model Specification

MHC Class II (I-A/I-E) -KO

Strain Name C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Catalog Number NM-KO-18032
Genetic Background C57BL/6Smoc
Synonyms Abeta, A beta, H-2Ab, H2-Ab, Ia2, Ia-2, IAb, I-Ab, I-Abeta, Rmcs1, Aalpha, A alpha, H-2Aa, Ia1, Ia-1, I-Aalpha, H-2Eb, Ia4, Ia-4, A130038H09Rik, H-2Eb2, Ia5, Ia-5, H-2Ea, Ia3, Ia-3, I-Ealpha
NCBI ID 14961, 14960, 14969, 381091, 100504404 ↗
MGI ID 103070, 95895, 95901, 95902, 95900 ↗
Ensembl ID ENSMUSG00000073421, ENSMUSG00000036594, ENSMUSG00000060586 , ENSMUSG00000067341, ENSMUSG00000036322 ↗
Strain State Embryo cryopreservation
Research Application immune system

Validation Data

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Fig.1 Detection of MHC Class II (I-A/I-E) expression in blood of female HO MHC Class II (I-A/I-E) -KO mice. 

Abbr.  WT, wild type; HO, homozygous.

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Fig.2 Detection of MHC Class II (I-A/I-E) expression in spleen of female HO MHC Class II (I-A/I-E) -KO mice. 

Abbr.  WT, wild type; HO, homozygous.

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Fig.3 Detection of immune cell subsets in blood and spleen of HO MHC Class II (I-A/I-E) -KO mice (two female mice in both groups).

Abbr.  WT, wild type; HO, homozygous.