Myl1-NLS-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200124

Strain Name : C57BL/6Smoc-Myl1em1(NLS-iCre-pA)Smoc

Gene Summary

Gene Name

Model Description

A NLS-iCre-pA expression cassette was knocked into the Myl1 gene start codon site via CRISPR/Cas9 mediated recombination.

Validation Data

NM-KI-200124-Myl1-NLS-Cre-1.png

Fig. 1 Cre-mediated recombination in the skeletal muscle of Myl1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the skeletal muscle of Myl1Cre/+; Rosa26tdTomato/+ mouse. 

NM-KI-200124-Myl1-NLS-Cre-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Myl1Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the skeletal muscle. Tdtomato expression can also be detected in individual cells derived from liver, myocardium and brown fat. Tdtomato expression can not be observed in the brain and stomach. (For more detailed information please contact our technical advisor.)

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