Nkx3-1-IRES-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-200071

Strain Name :

C57BL/6Smoc-Nkx3-1em1(IRES-CreERT2)Smoc

Gene Summary

Gene Name
  • Synonyms :

    Bax, NKX3A, NKX3.1, Nkx-3.1, bagpipe

  • NCBI ID :

    18095

  • MGI ID :

    97352

  • Ensembl ID :

    ENSMUSG00000022061

  • Strain State :

    胚胎冻存

Model Description

A IRES-CreERT2 expression cassette was knocked into the Nkx3-1 gene stop codon site.

Validation Data

image.png

Fig. 1 CreERT2-mediated recombination in the prostate of Nkx3-1CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the prostate lumen cells of Nkx3-1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. 

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of Nkx3-1CreERT2/+; Rosa26tdTomato/+ mice after tamoxifen treatment. Tdtomato was expressed in the prostate and individual cells of kidney. TdTomato can not be detected in the brain, thymus, retina, lung, liver, stomach, salivary gland, pancreas, colon, intestine, spleen, skin, testis and epididymis. (For more detailed information please contact our technical advisor.)


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