Strain Model Specification

Npy5r-KO

Strain Name C57BL/6Smoc-Npy5Rem1Smoc
Catalog Number NM-KO-190602
Genetic Background C57BL/6Smoc
Gene Symbol Npy5r
Synonyms Y5R, NPY5-R, NPYY5-R
NCBI ID 18168 ↗
MGI ID 108082 ↗
Ensembl ID ENSMUSG00000044014 ↗
Strain State Developing
Research Application The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma.