Strain Model Specification

R26-CAG-LSL-Luc-tdTomato

Strain Name C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Catalog Number NM-KI-18051
Genetic Background C57BL/6Smoc
Gene Symbol Gt(ROSA)26Sor
Synonyms R26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1
NCBI ID 14910 ↗
MGI ID 104735 ↗
Ensembl ID ENSMUSG00000086429 ↗
Strain State Repository Live

Validation Data

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Fig1. In the absence of any stimulation, the in vivo imaging system detected that R26-CAG-LSL-luci-tdTomato(+/-)；Dppa3-Cre (+/-) mice showed significant fluorescence.

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Fig2. The in vivo imaging system detected that R26-CAG-LSL-luci-tdTomato(+/-) mice showed some fluorescence. Some 'leaking' was found where luciferase were being expressed at a low level even without Cre.

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Fig. 3 Detection of tdTomato(red) in the liver, stomach, small intestine and large intestine of Dppa3Cre/+; Rosa26Luc-tdTomato/+ mice. 

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Fig. 4 Detection of tdTomato(red) in various tissues of Dppa3Cre/+; Rosa26Luc-tdTomato/+ mice. Tdtomato was expressed in the brain, eye, heart, spleen, kidney, pancreas, thymus, salivary glands, lung, skin, spinal cord, testis and epididymis. (For more detailed information please contact our technical advisor.)