Strain Model Specification

Raji-Luc

Strain Name Raji-Tg(luc)/Smoc
Catalog Number NM-B07-1
Genetic Background Raji

Validation Data

The Raji-Luc cell line is a Raji wild-type cell line with stable and high expression of Luciferase.  Luciferase activity was showed a steady increase in xenograft mouse models. This Raji-Luc cell line is available for in vivo imaging and assessment of novel therapeutic modalities.

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Figure 1. Morphology of Raji-Luc cell line.

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Figure 2. Luciferase activity assay of Raji-Luc cell lines.

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Figure 3. Average growth curves of Raji-Luc tumors in xenograft mouse models. (n=5) 

M-NSG (A) and hIL-15 M-NSG (B) mice were subcutaneously injected with Raji-Luc cells.

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Figure 4.  In vivo luciferase activity curves of Raji-Luc xenograft mouse models.  (n=5)

M-NSG mice (A, B) and hIL-15 M-NSG mice (C) were inoculated with Raji-Luc cells through tail vein injection.

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Figure 5.  Survival curves of Raji-Luc xenograft mouse models. (n=5)

M-NSG mice (A) were subcutaneously (s.c.) injected with Raji-Luc cells. While M-NSG mice (B) and hIL-15 M-NSG mice(C) were inoculated with Raji-Luc cells through tail vein injection.

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Figure 6. In vivo bioluminescence imaging of Raji-Luc xenograft mice.

M-NSG mice were subcutaneously (s.c.) injected with Raji-Luc cells.

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Figure 7. In vivo Raji-Luc tumor cell signal was inhibited by targeted drug in M-NSG mice. (n=5)