The Raji-Luc cell line is a Raji wild-type cell line with stable and high expression of Luciferase. Luciferase activity was showed a steady increase in xenograft mouse models. This Raji-Luc cell line is available for in vivo imaging and assessment of novel therapeutic modalities.
Figure 1. Morphology of Raji-Luc cell line.
Figure 2. Luciferase activity assay of Raji-Luc cell lines.
Figure 3. Average growth curves of Raji-Luc tumors in xenograft mouse models. (n=5)
M-NSG (A) and hIL-15 M-NSG (B) mice were subcutaneously injected with Raji-Luc cells.
Figure 4. In vivo luciferase activity curves of Raji-Luc xenograft mouse models. (n=5)
M-NSG mice (A, B) and hIL-15 M-NSG mice (C) were inoculated with Raji-Luc cells through tail vein injection.
Figure 5. Survival curves of Raji-Luc xenograft mouse models. (n=5)
M-NSG mice (A) were subcutaneously (s.c.) injected with Raji-Luc cells. While M-NSG mice (B) and hIL-15 M-NSG mice(C) were inoculated with Raji-Luc cells through tail vein injection.
Figure 6. In vivo bioluminescence imaging of Raji-Luc xenograft mice.
M-NSG mice were subcutaneously (s.c.) injected with Raji-Luc cells.
Figure 7. In vivo Raji-Luc tumor cell signal was inhibited by targeted drug in M-NSG mice. (n=5)
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