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Sftpc-IRES-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-18020

Strain Name :

C57BL/6Smoc-Sftpc^{em(IRES-CreERT2)Smoc}

Gene Summary

Gene Name

Synonyms :
SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
NCBI ID :
20389
MGI ID :
109517
Ensembl ID :
ENSMUSG00000022097
Strain State :
活体

Model Description

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

Validation Data

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Fig1. Cre mediated recombination in lung of SftpcCreERT2/+;Rosa26tdTomato/+ mouse.

Fig2. Detection of tdTomato(red) in various tissues of SftpcCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung epithelial cells, testis interstitial cells, salivary glands, muscles. Tissues that unexpressed include brain, spinal cord, retina, heart, liver, brown fat, thymus, kidney, pancreas, large and small intestine, spleen, and skin.(2-months old, male) (For more detailed information please contact our technical advisor.)

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