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Home / Tnfrsf1a/Tnfrsf1b-KO

Tnfrsf1a/Tnfrsf1b-KO

Background : C57BL/6Smoc

Catalog : NM-KO-18036

Strain Name : C57BL/6Smoc-Tnfrsf1aem1Smoc Tnfrsf1aem1Smoc

Gene Summary

Gene Name
  • Synonyms :

    CD120a, p55, p55-R, TNF-alphaR1, TNF-alpha-R1, TNFalpha-R1, TNFAR, Tnfr1, TNF-R1, TNF-R55, TNFR60, TNF receptor alpha chain, TNFRI, TNF-R-I, TNFRp55, CD120b, p75, p75 TNFR, TNF-alphaR2, TNFalpha-R2, TNFBR, Tnfr2, TNF-R2, TNF-R75, TNFR80, TNFRII, TNF-R-II

  • NCBI ID :

    21937 21938

  • MGI ID :

    1314884 1314883

  • Ensembl ID :

    ENSMUSG00000030341 ENSMUSG00000028599

  • Strain State :

    Embryo cryopreservation

Model Description

This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).
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  • h4-1BB(2) NM-HU-190077 1

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