Rat models carrying knock-in or transgenic fluorescent reporter genes for gene expression profiling and visual analysis, protein subcellular localization, and genetic lineage tracing.
Including: Cre recombinase, reporter gene, and Cas9-related rat
Immunodeficient rat models for xenografting (PDX, CDX), and cancer and cancer stem cell studies (ES/iPS), hematopoietic and immunological studies, and pharmacodynamic studies.
Humanized rats of drug target genes, such as humanized rats of immune checkpoint genes, for drug screening and drug efficacy evaluation, helping accelerate the development of drugs.
Rat models of human diseases for studying the role of genes in the inheritance, pathogenesis and progression of diseases.
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