U-GEMMs

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Zfp148em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-205103
Mice
Strain Name:C57BL/6Smoc-Zfp157em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp160em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp169em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp174em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-241379
Mice
Strain Name:C57BL/6Smoc-Zfp180em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp182em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp184em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp185em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Zfp189em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226425
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