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Rare Disease

Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.

Mice	Abcb4-KO(FVB) Strain Name：FVB-Abcb4^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-200584 Disease Connection：cholecystitis, cholestasis, hepatocellular carcinoma, intrahepatic cholestasis, primary sclerosing cholangitis
Mice	Abcc8-KO(2) Strain Name：C57BL/6Smoc-Abcc8^em2Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-225150
Mice	Abcd1-KO Strain Name：C57BL/6Smoc-Abcd1^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-2106014 Disease Connection：adrenoleukodystrophy
Mice	Abcg2-KO Strain Name：C57BL/6Smoc-Abcg2^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-18013 Disease Connection：erythropoietic protoporphyria, hyperuricemia
Mice	Abcg8-KO Strain Name：C57BL/6Smoc-Abcg8^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200906 Disease Connection：sitosterolemia
Mice	Acadl-KO Strain Name：C57BL/6Smoc-Acadl^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201235 Disease Connection：very long chain acyl-CoA dehydrogenase deficiency
Mice	Acadm-repeat(E8-10) Strain Name：C57BL/6Smoc-Acadm^{em1(E8-10 repeat)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-KI-200239 Disease Connection：medium chain acyl-CoA dehydrogenase deficiency
Mice	Acadvl-KO Strain Name：C57BL/6Smoc-Acadvl^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200908 Disease Connection：very long chain acyl-CoA dehydrogenase deficiency
Mice	Adh7-KO Strain Name：C57BL/6Smoc-Adh7^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201121 Disease Connection：Parkinson's disease
Mice	Agxt-KO Strain Name：C57BL/6Smoc-Agxt^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-210152 Disease Connection：primary hyperoxaluria type 1

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