U-GEMMs

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Ahcyl1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahcyl2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahdc1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:B6;129S-Ahi1tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00053
Research Application:Joubert syndrome
Mice
Strain Name:C57BL/6Smoc-Ahnakem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahrem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-200060
Research Application:Research on DAG and IP3 signal transduction and the development and heterogeneity of ILC family
Mice
Strain Name:C57BL/6Smoc-Ahrrem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahsa1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahsa2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ahsgem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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