In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
|
||
|
Strain Name:C57BL/6Smoc-Albem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2116165
|
|
|
||
|
Strain Name:C57BL/6Smoc-Alcamem(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230139
|
|
|
||
|
||
|
Strain Name:C57BL/6Smoc-Aldh1a3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-234889
|
|
|
||
|
||
|
Strain Name:C57BL/6Smoc-Aldh1l1em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-240585
|