U-GEMMs

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Anp32aem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:B6;129S-Anp32btm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00043
Mice
Strain Name:C57BL/6Smoc-Anp32eem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Antxr1em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-233904
Mice
Strain Name:C57BL/6Smoc-Antxr2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Antxrlem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Anxa1em2(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231267
Mice
Strain Name:C57BL/6Smoc-Anxa10em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-242853
Mice
Strain Name:C57BL/6Smoc-Anxa11em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Anxa2em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2105456
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