Xbp1-Flox

Nomenclature

C57BL/6Smoc-Xbp1^{em1(flox)Smoc}

Cat. NO.

NM-CKO-2101651

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Xbp1

Synonyms

TREB5， XBP-1， TREB-5， D11Ertd39e

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

XBP1

Model Description

These mice carry loxP sites flanking exon 2 of Xbp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Xbp1 gene.

*Literature published using this strain should indicate: Xbp1-Flox mice (Cat. NO. NM-CKO-2101651) were purchased from Shanghai Model Organisms Center, Inc..

Disease Connection

Inflammatory Bowel Disease

Phenotype(s)

MGI:5441532
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Vil1-cre mice.

Reference(s)

Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS, XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 2008 Sep 5;134(5):743-56

Paxbp1-Flox Strain Name：C57BL/6Smoc-Paxbp1^em^1(flox)^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-234709
Paxbp1-KO Strain Name：C57BL/6Smoc-Paxbp1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Stxbp1-KO Strain Name：C57BL/6Smoc-Stxbp1^em¹^Smoc Strain State：Developing \| Cat. NO.：NM-KO-241571
Stxbp1-Flox Strain Name：C57BL/6Smoc-Stxbp1^{tm1(flox)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-CKO-200238
Xbp1-KO Strain Name：C57BL/6Smoc-Xbp1^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-232760

U-GEMMs

Other Models

Models

Xbp1-Flox

Gene Summary

Model Description

Disease Connection

You may also like

U-GEMMs

Other Models

Models

Xbp1-Flox

Gene Summary

Model Description

Disease Connection

Related Strain(s)

You may also like