hIL12B
Nomenclature
C57BL/6Smoc-Il12betm3(hIL12B)/Smoc
Cat. NO.
NM-HU-2000057
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Il12b
Model Description
Validation Data
Fig1. Detection of IL12B expression in thymus by RT-PCR.
Wild type: only one band at 260 bp with primers F1/R1(mIl12b);
Heterozygous: one band at 260 bp with primers F1/R1(mIl12b) and one band at 260 bp with primers F2/R2(hIL12B);
Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Detection of hIL12B expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Note. hIL12B and C57BL/6 mice were i.p. injected with LPS(10mg/kg) for 2h.
Fig 3. Detection of mIL12B expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Note. hIL12B and C57BL/6 mice were i.p. injected with LPS(10mg/kg) for 2h.
Fig4. Detection of human IL12P70 and mouse IL12P70 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hIL12A/hIL12B and C57BL/6 mice were i.p. injected with LPS for 2h.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
