Ptpn11-Flox

Nomenclature

C57BL/6Smoc-Ptpn11em1(flox)Smoc

Cat. NO.

NM-CKO-231881

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Ptpn11

Model Description

These strains carry loxP sites flanking exon 4 of Ptpn11 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ptpn11 gene.

Disease Connection

Juvenile Myelomonocytic Leukemia
Noonan Syndrome 1
Disease Of Metabolism

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