Sh3rf2-KO

Nomenclature

C57BL/6Smoc-Sh3rf2em1Smoc

Cat. NO.

NM-KO-190449

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Sh3rf2

Synonyms

RNF158; Ppp1r39; AI452083; 2310046K19; 9130023G24Rik

NCBI ID

269016

MGI ID

2444628

Ensembl ID

ENSMUSG00000057719

Pubmed

Sh3rf2

Human Ortholog

SH3RF2

Model Description

exon5 of Sh3rf2 gene was deleted to generate Sh3rf2 knockout mice.
Research Application：Autism

Disease Connection

Autism Spectrum Disorder

Phenotype(s)

MGI:6430623

Reference(s)

Wang S, Tan N, Zhu X, Yao M, Wang Y, Zhang X, Xu Z, Sh3rf2 Haploinsufficiency Leads to Unilateral Neuronal Development Deficits and Autistic-Like Behaviors in Mice. Cell Rep. 2018 Dec 11;25(11):2963-2971.e6

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