R26-LSL-SmoM2W539L-IRES-tdTomato

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA)Smoc

Cat. NO.

NM-KI-200035

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Synonyms

R26，ROSA26，AV258896，Gtrgeo26，Gtrosa26，Thumpd3as1

NCBI ID

14910

MGI ID

104735

Ensembl ID

ENSMUSG00000086429

Pubmed

Gt(ROSA)26Sor

Model Description

These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence.
Research Application：Medulloblastoma

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