Ppm1k-KO

Nomenclature

C57BL/6Smoc-Ppm1kem1Smoc

Cat. NO.

NM-KO-201326

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ppm1k

Synonyms

PP2Cm， PP2C-kappa， 2900063A19Rik， A930026L03Rik

NCBI ID

243382

MGI ID

2442111

Ensembl ID

ENSMUSG00000037826

Pubmed

Ppm1k

Human Ortholog

PPM1K

Model Description

Exon 3 of Ppm1k gene was deleted to generate Ppm1k knockout mice.

Disease Connection

Maple Syrup Urine Disease

Phenotype(s)

MGI:3850972

Reference(s)

Lu G, Sun H, She P, Youn JY, Warburton S, Ping P, Vondriska TM, Cai H, Lynch CJ, Wang Y, Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest. 2009 Jun;119(6):1678-87

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