Sgcd-KO

Nomenclature

C57BL/6Smoc-Sgcdem1Smoc

Cat. NO.

NM-KO-201205

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Sgcd

Synonyms

35DAG， AI504364， AW547581， SG-delta， delta-SG， A530047J11Rik

NCBI ID

24052

MGI ID

1346525

Ensembl ID

ENSMUSG00000020354

Pubmed

Sgcd

Human Ortholog

SGCD

Model Description

Exon 4 of Sgcd gene was deleted to generate Sgcd knockout mice.

Disease Connection

Dilated Cardiomyopathy 1L

Phenotype(s)

MGI:3618464

Reference(s)

Coral-Vazquez R, Cohn RD, Moore SA, Hill JA, Weiss RM, Davisson RL, Straub V, Barresi R, Bansal D, Hrstka RF, Williamson R, Campbell KP, Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy. Cell. 1999 Aug 20;98(4):465-74

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