Uox-Flox/Alb-Cre

Model Description

The Uox-Flox was crossed with Alb-Cre to generate Uox-Flox/Alb-Cre mice.

*Literature published using this strain should indicate: Uox-Flox/Alb-Cre mice (Cat. NO. NM-XA-242357) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig 1. Effect of Allopurinol on Serum Uric Acid Levels. 6 week-old Uox-Flox/Alb-Cre male mice were Treated with Allopurinol. Compared to C57BL/6, serum uric acid levels of Uox-Flox/Alb-Cre male mice were significantly elevated. Treatment with allopurinol (100mg/kg) significantly reduced serum uric acid levels in Uox-Flox/Alb-Cre male mice (n=10). Values are expressed as mean ± SEM.

Abbr. WT, wild type.

Fig 2. Body Weight Comparison. The body weight of Uox-Flox/Alb-Cre male mice was lower compared to C57BL/6 mice. Allopurinol treatment had no effect on body weight (n=10). Values are expressed as mean ± SEM.

Fig 3. Kidney Function Assessment. Kidney function in Uox-Flox/Alb-Cre male mice showed no significant difference compared to C57BL/6 mice (n=10). Values are expressed as mean ± SEM.

Related Strain(s)

1110025M09Rik-S6x Strain Name：C57BL/6Smoc-1110025M09Rik^em(S6X)Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KI-215102
1110038F14Rik-KO Strain Name：C57BL/6Smoc-1110038F14Rik^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-232645
1110038F14Rik-Flox Strain Name：C57BL/6Smoc-1110038F14Rik^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-226005
1300017j02Rik-KO Strain Name：C57BL/6Smoc-1300017j02Rik^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190231
1600012H06Rik-KO Strain Name：C57BL/6Smoc-1600012H06Rik^em1/Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-230418

1110025M09Rik-S6x Strain Name：C57BL/6Smoc-1110025M09Rik^em(S6X)Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KI-215102
1110038F14Rik-KO Strain Name：C57BL/6Smoc-1110038F14Rik^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-232645
1110038F14Rik-Flox Strain Name：C57BL/6Smoc-1110038F14Rik^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-226005
1300017j02Rik-KO Strain Name：C57BL/6Smoc-1300017j02Rik^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190231
1600012H06Rik-KO Strain Name：C57BL/6Smoc-1600012H06Rik^em1/Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-230418

U-GEMMs

Other Models

Models

Uox-Flox/Alb-Cre

Model Description

Validation Data

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