Ucp2-KO

Nomenclature

B6;129S-Ucp2tm1Smoc

Cat. NO.

NM-KO-00038

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ucp2

Synonyms

Slc25a8

NCBI ID

22228

MGI ID

109354

Ensembl ID

ENSMUSG00000033685

Pubmed

Ucp2

Human Ortholog

UCP2

Model Description

Homozygous null mutants may have elevated pancreatic islet cell ATP levels and increased glucose-stimulated secretion of insulin.
Research Application：nervous system,immune system

Disease Connection

Polycystic Liver Disease

Phenotype(s)

MGI:6285862

Reference(s)

Hirose M, Schilf P, Rohde S, Gupta Y, Sancerni T, Alves-Guerra MC, Sina C, Jaster R, Miroux B, Ibrahim SM, The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice. Mitochondrion. 2018 Sep;42:50-53

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