hIl5

Nomenclature

C57BL/6Smoc-Il5tm3(hIL5)Smoc

Cat. NO.

NM-HU-190001

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
IL5

Synonyms

Il-5

NCBI ID

16191

MGI ID

96557

Ensembl ID

ENSMUSG00000036117

Pubmed

IL5

Human Ortholog

IL5

Model Description

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.
Research Application：Immune-related

Validation Data

image.png

Fig1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL5-Hu.png

Fig 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

IL5-Mu.png

Fig 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

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