hIL18BP

Nomenclature

C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc

Cat. NO.

NM-HU-210039

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Il18bp

Model Description

The endogenous mice Il18bp gene was replaced by human IL18BP gene.
Research Application:inmmue therapy;drug screening

Validation Data

image.png

Fig1. Detection of IL18BP expression in thymus and liver by RT-PCR. Wild type: only one band at 354 bp with primers F1/R1(mIl18bp);Heterozygous: one band at 354 bp with primers F1/R1(mIl18bp) and one band at 220 bp with primers F2/R2(hIL18BP); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of IL18BP expression in thymus and liver by RT-PCR.  Wild type: only one band at 354 bp with primers F1/R1(mIl18bp); Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP);  Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig3. Detection of hIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig4. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig5. Detection of hIL18BP expression in serum by ELISA (n=3). Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png


Fig6. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more