hCD93

Nomenclature

C57BL/6Smoc-Cd93em1(hCD93)Smoc

Cat. NO.

NM-HU-215065

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Cd93

Model Description

The endogenous mouse Cd93 gene was replaced by human CD93 gene.

Validation Data

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Fig1. Detection of CD93 expression in lung by RT-PCR. Wild type: only one band at 273 bp with primers F1/R1(mCd93);Heterozygous: one band at 273 bp with primers F1/R1(mCd93) and one band at 129 bp with primers F2/R2(hCD93); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of hCD93 expression on endothelial cells in lung in hCD93 KI mice.

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Fig3. Detection of hCD93 expression on macrophages, monocytes and neutrophils in blood in hCD93 KI mice.

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Fig4. Detection of hCD93 expression on macrophages, monocytes and neutrophils in spleen in hCD93 KI mice.

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Fig5. Detection of hCD93 expression on macrophages, monocytes and neutrophils in bone morrow in hCD93 KI mice.


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