hHER3(2)
Nomenclature
C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Cat. NO.
NM-HU-225068
Strain State
Repository Live
Gene Summary
Gene Symbol
Erbb3
Model Description
The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.
Validation Data
Fig.1 Detection of ERBB3 expression in colon by RT-PCR.
Wild type: only one band at 343 bp with primers F1/R1(mErbb3);
Homozygous: only one band at 305 bp with primers F2/R2(hERBB3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human hHER3 expression in hHER3(2) knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, MC38-hHER3 cells.
Note. The anti-human hHER3 antibody cross-reacted with mouse hHER3 and humanized hHER3.
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