hSERPINC1

Nomenclature

C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc

Cat. NO.

NM-HU-225075

Strain State

Repository Live

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Gene Summary

Gene Symbol
Serpinc1

Synonyms

At3; At-3; ATIII; AI114908

NCBI ID

11905

MGI ID

88095

Ensembl ID

ENSMUSG00000026715

Pubmed

Serpinc1

Human Ortholog

SERPINC1

Model Description

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

Validation Data

image.png

Fig1. Detection of SERPINC1 expression in liver by RT-PCR. 

Wild type: only one band at 250 bp with primers F1/R1 (mSerpinc1);

Homozygous: only one band at 374 bp with primers F2/R2 (hSERPINC1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of hSERPINC1(A) and mSERPINC1(B) expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig3. Detecion of coagulation time in hSERPINC1 knockin mice by APTT(n=3). 

Abbr. HO, homozygous; WT, wild type.



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