hFCGRT(NMG）
Nomenclature
NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
Cat. NO.
NM-NSG-020
Strain State
Repository Live
Gene Summary
Gene Symbol
Fcgrt
Model Description
The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.
Validation Data
Fig.1 Detection of FCRN expression in kidney by RT-PCR.
Wild type: only one band at 181 bp with primers F1/R1(mFcgrt);
Heterozygous: one band at 181 bp with primers F1/R1(mFcgrt) and one band at 310 bp with primers F2/R2(hFCGRT).
Abbr. M, DNA marker; HE, heterozygous; WT, wild type.
Fig.2 Detection of human FCRN expression in hFCRN (NMG) mice by WB.
Abbr. M, marker; WT1, wild type, NOD-Scid; WT2, wild type, NMG; HE, heterozygous; PC, positive control, hFCRN (NM-HU-190070).
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