hCTLA-4/hCD28(BALB/c)

Nomenclature

BALB/cAnSmoc-Ctla4^em1(hCTLA4)Cd28^{em1(hCD28)Smoc}

Cat. NO.

NM-HU-200226

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
CD28

Synonyms

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

CD28

Gene Symbol
CTLA4

Synonyms

Cd152; Ly-56; Ctla-4

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

CTLA4

Show moreShow less

Model Description

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.

Research Application：Immunotherapy

*Literature published using this strain should indicate: hCTLA-4/hCD28(BALB/c) mice (Cat. NO. NM-HU-200226) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig1. Analysis of human CTLA4(hCD152) expression in the spleen by FACS . The homozygous KI mouse expresses human CTLA4 on T cells.

Fig2. Analysis of human CD28 expression in the spleen by FACS . The homozygous KI mouse expresses human CD28 on T cells.

hCD24/hSIGLEC10 Strain Name：C57BL/6Smoc-Cd24a^tm1(hCD24)Siglecg^{tm1(hSIGLEC10)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-210367
hB7H3/hCD28 Strain Name：C57BL/6Smoc-Cd276^tm2(hCD276)Cd28^{em2(hCD28)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-210353
hCD28(BALB/c,3) Strain Name：BALB/cAnSmoc-Cd28^{em(hCD28)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220509
hCD28 Strain Name：C57BL/6Smoc-Cd28^{em2(hCD28)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-190011
Cd28-KO Strain Name：C57BL/6Smoc-Cd28^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-190034

U-GEMMs

Other Models

Models

hCTLA-4/hCD28(BALB/c)

Gene Summary

Model Description

Validation Data

You may also like

U-GEMMs

Other Models

Models

hCTLA-4/hCD28(BALB/c)

Gene Summary

Model Description

Validation Data

Related Strain(s)

You may also like