hIL17A

Nomenclature

C57BL/6Smoc-Il17atm1(hIL17A)/Smoc

Cat. NO.

NM-HU-00042

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
IL17A

Model Description

The endogenous mouse Il17a gene was replaced by human IL17A gene.
Research Application:Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig1. Detection of IL-17A expression in Large Intestine by RT-PCR. Wild type: only one band at 100 bp with primers F1/R1(mIl-17a);Homozygous: only one band at 121 bp with primers F2/R2(hIL-17A); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL17A.png

Fig2. Expression of human IL17A in cell supernatant derived from splenocytes  of IL17A-HU homozygous mice is detected by Elisa.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more