hTIGIT(BALB/c,2)
Nomenclature
BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
Cat. NO.
NM-HU-200245
Strain State
Repository Live
Gene Summary
Gene Symbol
Tigit
Model Description
The endogenous mice Tigit gene was replaced by human TIGIT gene.While hTIGIT(BALB/c) (Stock No.NM-HU-2000043) have been pulled from shelves for some reasons.
Validation Data
Fig.1 Detection of TIGIT expression in large intestine by RT-PCR.
Wild type: only one band at 126 bp with primers F1/R1(mTigit);
Homozygous: only one band at 168 bp with primers F2/R2(hTIGIT).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hTIGIT expression on splenocytes-derived activated T cells in hTIGIT KI mice.
Note. Splenocytes from BALB/c and HO hTIGIT mice were stimulated with ConA in vitro.
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