hCD40/hCD40L

Nomenclature

C57BL/6Smoc-CD40em2(hCD40)Cd40lgtm1(hCD40L)/Smoc

Cat. NO.

NM-HU-200268

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CD40

Gene Symbol
Cd40lg

Model Description

hCD40(NM-HU-00076)was crossed with hCD40L(NM-HU-2000033)to generate hCD40/hCD40L mice

Validation Data

image.png

Fig1. Detection of CD40 expression in spleen, lung and thymus by RT-PCR. Wild type: only one band at 338 bp with primers F1/R1(mCd40);Homozygous: only one band at 255 bp with primers F2/R2(hCD40); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of CD40L expression in spleen, lung and thymus by RT-PCR. Wild type: only one band at 266 bp with primers F1/R1(mCd40l);Homozygous: only one band at 257 bp with primers F2/R2(hCD40L); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.


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