hCD28(BALB/c,3)

Nomenclature

BALB/cAnSmoc-Cd28em(hCD28)Smoc

Cat. NO.

NM-HU-220509

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
CD28

Synonyms

NCBI ID

12487

MGI ID

88327

Ensembl ID

ENSMUSG00000026012

Pubmed

CD28

Human Ortholog

CD28

Model Description

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Validation Data

image.png

Fig1. Detection of hCD28 expression on T cells in blood in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig2. Detection of hCD28 expression on T cells in spleen in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig3. Detection of hCD28 expression on T cells in thymus in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more