hMTARC1

Nomenclature

C57BL/6Smoc-Mtarc1tm1(hMTARC1)Smoc

Cat. NO.

NM-HU-234117

Strain State

Repository Live

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Model Description

The endogenous mouse Mtarc1 gene was replaced by human MTARC1 gene.

Validation Data

image.png

Fig.1 Detection of MTARC1 expression in liver by RT-PCR. 

Wild type: only one band at 211 bp with primers F1/R1(mMtarc1);

Heterozygous: one band at 211 bp with primers F1/R1(mMtarc1) and one band at 211 bp with primers F2/R2(hMTARC1). 

Abbr. M, DNA marker;  HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human MTARC1 expression in hMTARC1 Mice by WB. 

Abbr. M,marker;WT, wild type;HE,heterozygote;PC,positive control,HepG2 cell.

Note. The anti-human MTARC1 Antibody cross-reacted with mouse MTARC1 and humanized MTARC1.Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.


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