hMRGPRX2
Nomenclature
C57BL/6Smoc-Mrgprb2em1(hMRGPRX2)Smoc
Cat. NO.
NM-HU-234361
Strain State
Repository Live
Gene Summary
Gene Symbol
Mrgprb2
Model Description
The endogenous mouse Mrgprb2 gene was replaced by human MRGPRX2 gene.
Validation Data
Fig.1 Detection of MRGPRX2 expression in bladder by RT-PCR.
Wild type: only one band at 265 bp with primers F1/R1 (mMrgprb2);
Homozygous: only one band at 383 bp with primers F2/R2 (hMRGPRX2).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Characterization of MRGPRX2 (X2) Expression. huX2 immunoreactivity was observed in flow isolated peritoneal mast cells (PMCs) from X2-KI but not WT control mice or staining controls (isotype CTR). (Data from a collaborator)
Fig.3 MRGPRX2 is not expressed on macrophages (as expected). (Data from a collaborator)
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