hMRGPRX2(BALB/c)

Nomenclature

BALB/cAnSmoc-Mrgprb2em1(hMRGPRX2)Smoc

Cat. NO.

NM-HU-234362

Strain State

Developing

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Gene Summary

Gene Symbol
Mrgprb2

Model Description

The endogenous mouse Mrgprb2 gene was replaced by human MRGPRX2 gene.

Validation Data

image.png

Fig.1 Detection of MRGPRX2 expression in bladder by RT-PCR. 

Wild type: only one band at 265 bp with primers F1/R1 (mMrgprx2);

Heterozygous: one band at 265 bp with primers F1/R1 (mMrgprx2) and one band at 383 bp with primers F2/R2 (hMRGPRX2). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.


image.png

Fig.2 Detection of hMRGPRX2 expression on mast cells in het hMRGPRX2 KI mice


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