hANGPTL3(3)

Nomenclature

C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc

Cat. NO.

NM-HU-210037

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Angptl3

Synonyms

hypl

NCBI ID

30924

MGI ID

1353627

Ensembl ID

ENSMUSG00000028553

Pubmed

Angptl3

Human Ortholog

ANGPTL3

Model Description

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.
Research Application：inmmue therapy；drug screening

Validation Data

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Fig1. Detection of ANGPTL3 expression in liver by RT-PCR. Wild type: only one band at 208 bp with primers F1/R1 (mAngptl3); Heterozygous: one band at 208bp with primers F1/R1 (mAngptl3) and one band at 325 bp with primers F2/R2 (hANGPTL3); Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hANGPTL3 and mANGPTL3 expression in serum by ELISA. Abbr. HO, homozygous; WT, wild type.

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