hDDR1

Nomenclature

C57BL/6Smoc-Ddr1tm1(hDDR1)Smoc

Cat. NO.

NM-HU-225086

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Ddr1

Model Description

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.


Validation Data

image.png

Fig.1 Detection of DDR1 expression in ovary by RT-PCR. 

Wild type: only one band at 401 bp with primers F1/R1(mDdr1);

Homozygous: only one band at 177 bp with primers F2/R2(hDDR1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human DDR1 expression in hDDR1 knockin Mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, hela cells.

Note. The anti-human DDR1 Antibody cross-reacted with mouse DDR1 and humanized DDR1.


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