hDLL3

Nomenclature

C57BL/6Smoc-Dll3em1(hDLL3)Smoc

Cat. NO.

NM-HU-200231

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
Dll3

Model Description

The endogenous mice Dll3 gene was replaced by human DLL3 gene.

Validation Data

image.png

Fig.1 Detection of DLL3 expression in brain by RT-PCR. 

Wild type: only one band at 293 bp with primers F1/R1 (mDll3);

Homozygous: only one band at 282 bp with primers F2/R2 (hDLL3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human DLL3 expression in hDLL3 knockin mice by WB. 

Abbr. HO, homozygous; WT, wild type.

Note: The anti-human DLL3 antibody cross-reacted with mouse DLL3 and humanized DLL3.



You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more