hHLA-DPB1*04: 01

Nomenclature

C57BL/6Smoc-H2-Ab1em1(hHLA-DPB1*04: 01)/Smoc

Cat. NO.

NM-HU-210011

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
H2-Ab1

Gene Symbol
H2-Ab1

Model Description

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.
Research Application:inmmue therapy;drug screening

Validation Data

image.png

Fig1. Detection of HLA-DPB1*04:01 expression in spleen by RT-PCR. Wild type: only one band at 372 bp with primers F1/R1(mH2-Ab1);Heterozygous: one band at 372 bp with primers F1/R1(mH2-Ab1) and one band at 362 bp with primers F2/R2(hHLA-DPB1*04:01); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more