SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
Mice
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Strain Name:C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000019
Research Application:Immunotherapy,drug screening
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