hPD-1/hICOS(2)

Nomenclature

C57BL/6Smoc-Pdcd1^em1(hPDCD1)Icos^{em1(hICOS)Smoc}

Cat. NO.

NM-HU-2000100

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
ICOS

Synonyms

AILIM; CCLP; CRP-1; H4; Ly115

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

ICOS

Gene Symbol
Pdcd1

Synonyms

PD-1; Pdc1; Ly101

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

PDCD1

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Model Description

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Research Application：Immunotherapy,cancer research,drug screening

*Literature published using this strain should indicate: hPD-1/hICOS(2) mice (Cat. NO. NM-HU-2000100) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig1. Detection of PD1 expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

Fig2. Detection of human ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

Fig3. Detection of mouse ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

hICOS(BALB/c) Strain Name：BALB/cAnSmoc-Icos^{em1(hICOS)/Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-2000046
Icos-Flox Strain Name：C57BL/6Smoc-Icos^{tm1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-2103362
hICOS(2) Strain Name：C57BL/6Smoc-Icos^{em2(hICOS)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-190030
Icos-KO Strain Name：C57BL/6Smoc-Icos^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190093
hICOS Strain Name：C57BL/6Smoc-Icos^{em1(hICOS)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-00052

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Models

hPD-1/hICOS(2)

Gene Summary

Model Description

Validation Data

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U-GEMMs

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Models

hPD-1/hICOS(2)

Gene Summary

Model Description

Validation Data

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